Answer
Oct 08, 2026 - 10:09 AM
Brilinta interacts with strong CYP3A4 inhibitors and inducers (such as nefazodone, ritonavir, phenobarbital), opioids, seizure medications (carbamazepine, phenytoin), tuberculosis drugs (rifampin), antifungals (ketoconazole, itraconazole, voriconazole), antibiotics (clarithromycin), other blood thinners (warfarin, clopidogrel), cholesterol drugs (simvastatin, lovastatin), heart drugs (digoxin), HIV protease inhibitors (atazanavir), NSAIDs (ibuprofen, naproxen), and grapefruit juice. Knowing these interactions helps avoid reduced efficacy or increased side effects; CYP3A4 is a liver enzyme involved in metabolizing many drugs.
