What is the biggest side effect of amitriptyline?
Amitriptyline Hydrochloride
Medications
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Open Oct 08, 2026 - 09:50 AM
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Oct 08, 2026 - 09:50 AM
The biggest side effect of amitriptyline is drowsiness or sedation, which can make people feel very sleepy or tired. Other common side effects include dry mouth, constipation, and weight gain. However, drowsiness is typically the most prominent and noticeable effect for most patients.
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