What is the best tricyclic antidepressant for OCD?
Anafranil
Medications
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Open Jul 14, 2026 - 11:26 AM
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Jul 14, 2026 - 11:26 AM
The best tricyclic antidepressant for OCD is clomipramine. It is considered the most effective TCA for obsessive-compulsive disorder due to its strong serotonergic activity. Other TCAs are generally less effective for OCD.
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