Answer
Apr 27, 2026 - 12:24 PM
Interactions can occur with MAOIs (such as isocarboxazid, linezolid, IV methylene blue, phenelzine, rasagiline, tranylcypromine, selegiline), norepinephrine, meperidine, phenobarbital, phenytoin, serotonergic agents (SSRIs, SNRIs, triptans, TCAs, fentanyl, lithium, tramadol, tryptophan, buspirone, paroxetine, fluoxetine, St. John’s Wort), CYP2D6 inhibitors (such as quinidine, ritonavir), and medications that alter urine pH (like ascorbic acid, ammonium chloride, sodium bicarbonate, acetazolamide, some thiazide diuretics). Understanding interactions can prevent dangerous side effects and ensure the medication works as intended.
