Answer
Apr 27, 2026 - 11:49 AM
Prozac interacts with many medications, including other antidepressants (like SNRIs or tricyclics), buspirone, desipramine, lithium, tryptophan, St. John’s Wort, blood thinners (warfarin, Coumadin, Jantoven), ADHD medications (Adderall, Concerta, Ritalin, Vyvanse, Zenzedi), migraine medications (rizatriptan, sumatriptan, zolmitriptan), opioids (fentanyl, tramadol), and NSAIDs (aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam). Discussing your medication list with your doctor helps avoid harmful interactions and ensures your treatment plan is safe.
