Answer
Apr 21, 2026 - 11:11 AM
Estraderm has boxed warnings for increased risks of endometrial cancer, stroke, heart attack, blood clots, breast cancer, and probable dementia, especially in women over 65. Estrogen-alone therapy increases endometrial cancer risk, so progestin may be prescribed. Boxed warnings highlight serious risks so you can make informed choices and work closely with your healthcare provider.
